ISSN: (Online) 2321 -4155
ISSN: (Print) 2320 -7000

CARCINOGENICITY OF BENZOTHIAZYL-2 - CYCLOHEXYLSULFENAMIDE AND CYCLOHEXIMIDE ON DEVELOPMENT OF Drosop

ABSTRACT

 

Amides are used as industrial chemicals, including in the manufacture of synthetic fibers and nylon. Amides are also used as pesticides and drugs. Different living animal models are being used for bio-monitoring of many toxic chemicals including mammals. The fruit fly, Drosophila melanogaster, has been extensively studied for over a century as a model organism. In the present study, both genotoxic and non-genotoxic mode of action on two amide group of chemical was conducted by investigating extensively with three different parameters of developmental, morphological and chromosomal changes. This has been undertaken for the first time using Drosophila melanogaster asliving biological model forits carcinogenic potentialities

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